Post author By Julieanne Post date December 28, 2015 Home » Attractions » Hernando de Soto – Natchez Trace Parkway – MS Milepost 243.3 – Hernando de Soto – Spanish explorer of the Mississippi spent the winter of 1540 – 1541 near here. ← Monroe Mission – Natchez Trace Parkway – MS → Davis Lake – Natchez Trace Parkway – MS